康妇特栓联合阿奇霉素治疗女性非淋菌性尿道炎效果观察

Fffects of azithromycin combined with Kangfute suppository on patients with nongonococcal urethritis

目的观察康妇特栓联合阿奇霉素对支原体和衣原体引起的非淋菌性尿道炎的临床效果。方法将83例女性非淋菌性尿道炎患者随机分为治疗组(43例)和对照组(40例),治疗组每日静脉点滴乳糖酸阿奇霉素0.5g/d,同时使用康妇特栓1剂/d;对照组单用乳糖酸阿奇霉素静脉注射0.5g/s。连续治疗7d后,观察临床症状及衣原体和支原体转阴率。结果联合用药对单纯性衣原体或支原体感染及衣原体、支原体混合感染都有很好的转阴效果,转阴率分别达到92.3%、90.1%和83.3%,能有效消除或减轻临床症状及体征,其疗效显著优于单独使用阿奇霉素(P<0.05)。结论康妇特栓与阿奇霉素联合是行之有效的治疗女性非淋菌性尿道炎的治疗方案。

Objective To observe the clinical effects f azithromycin combined with kangfute suppository on nongonoeoccal urethritis patients with Chlamydia and Mycoplasma infection. Methods There 83 patients with nongonococeal urethritis were randomly divided into treatment group, treated with intravenous drip of lactose-azithromycin （0.5g/day）, in addition, kangfute suppository was used QD and control group treated with intravenous drip of lactose-azithromycin （0.5g/day） alone. Seven days after treatment, the clinical symptoms and the pathogen negative conversion rate were recorded. Results A high negative conversion rate could be obtained by combined use of azithmmyein and Kangfute suppository in simple Chlamydia or Mycoplasma infection and mixed Chlamydia and Mycoplasma infection, being 92.3%,90.1% and 83.3%, respectively,higher than that with azithromycin alone. Conclusion The combination of azithromyein and Kangfute suppository is an effective therapeutic means on nongonoeoccal urethritis due to Chlamydia and Mycoplasma infection.