摘要
目的:比较齐拉西酮与阿立哌唑对精神分裂症的临床疗效。方法:将60例精神分裂症患者随机分为齐拉西酮组(30例)和阿立哌唑组(30例),疗程8周,在治疗前及治疗后第2、4、6、8周末采用阳性阴性症状量表(PANSS)、不良反应量表(TESS)及锥体外系副反应量表(RSESE)评定其疗效及药物不良反应。结果:齐拉西酮显效率为63.3%,阿立哌唑显效率为60%,两组疗效差异无显著性。不良反应程度均较轻,且不良反应发生率无明显差异。结论:齐拉西酮与阿立哌唑治疗精神分裂症均有效,且疗效相当,依从性好。
Objective：To investigate the clinical effects and safety of Ziprasidon and Aripiprazole for treating schizophrenia. Methods：A total of 60 patients with schizophrenia were randomly divided into Ziprasidon group and Aripiprazole group.The treatment duration was eight weeks.PANSS TESS and RSESE were used to evaluate the clinical effects and side-effect respectively before treatment and on the 2nd,4th,6th and 8th weekend of after treatment.Results： The effective rate of Ziprasidon and Aripiprazole were 63.3% and 60% respectively,which showed no significant difference.There was no severe side effect in both groups.The incidence of adverse effects in two groups had no significant difference and the side effects of both groups were less.Conclusions： Ziprasidon and Aripiprazole are effective in the treatment of schizophrenia.Both have good compliance and few adverse effects.
出处
《中国民康医学》
2008年第23期2760-2761,共2页
Medical Journal of Chinese People’s Health
