徐州矿区成人代谢综合征的流行病学研究

Epidemiological Study of Metabolic Syndrome in Xuzhou Mining Area

目的了解徐州矿区人群代谢综合征(metabolic syndrome,MS)的患病率及流行特征。方法采用分层随机整群抽样方法调查徐州矿区20岁及20岁以上的常住(>5年)居民共560人(男214人,女346人),进行问卷调查、体格检查及相关代谢指标的测定。MS主要采用2004年中华医学会糖尿病学分会(CDS)的诊断标准。结果徐州矿区成人所查人群中男性及女性MS的粗患病率分别为27.57%和7.23%,男性患病率显著高于女性(P<0.05),并随年龄的增长而显著升高(P<0.05);超重或肥胖、空腹血糖升高、血压升高(≥140/90mm Hg)、甘油三酯(TG)升高或高密度脂蛋白(HDL)降低在MS患者中的发生率分别为78.57%、83.33%、72.62%和95.24%。MS患者中有3个组分异常的占70.24%,而4个组分均异常的占29.76%。结论徐州矿区成年人群MS患病率较高,男性、老年人是MS的高危人群。

Objective To describe the prevalence rate and characters of metabolic syndrome （MS） in Xuzhou mining areas. Methods 560 residents（214 male cases and 346 female cases） who was more than 20 years old and lived in mining areas of Xuzhou at least five years were enrolled in this survey. Stratified random cluster sampling was used to investigate the prevalence of MS（ CDS criterion ,2004）. The physical examination and relative metabolism indes, such as fasting plasma glucose, triglycerides （TG） and high density lipoprotein-C （HDL-C）, were measured. Results The crude prevalence rate of MS was 27.57% and 7.23% in male and female respectively. Male and aged people were the population at high risk of MS. The overweight or obesity, abnormal fasting plasma glucose or diabetes mellitus （ DM ）, hypertension （≥ 140/90 mm Hg）, hypertriglyceridemia or hypoalphalipoproteinemia-C accounted for 78.57% ,83.33% ,72.62% and 95.24% respectively in MS individuals, of which 70.24% incorporated three metabolic abnormities and 29.76% had four metabolic abnormities. Conclusions The prevalence rate of MS in Xuzhou mining area was very high. Old and male people were at higher risk.