52例早期梅毒诊疗分析

Analysis on diagnosis and treatment of 52 patients with early syphilis

目的了解濮阳市早期梅毒的患病情况,总结临床治疗经验,降低误诊率。方法严格按照卫生部防疫司《性病防治手册》中诊断及分析标准,进行实验室梅毒螺旋体抗体吸收试验(FTA-ABS)、梅毒螺旋体被动乳胶凝集试验(TPPA)血清学检查。结果性活跃人群(20～40岁)、个体供销和服务人员梅毒患病率分别为86.1%和67.3%,误诊率为23.1%;传染源以婚外异性性伴为主。结论性活跃人群(20～40岁)、个体供销和服务人员为梅毒感染的高危人群,应加强这类人群的监测工作;为避免较高的误诊率,对疑似患者应主动进行TPPA梅毒血清学检查工作;传染源多为异性性伴,预示应不断提高社会的监管力度,切实有效地进行健康教育干预。

Objective To find out the state of early syphilis in our city,to summarize the clinical treatment experience,and so as to reduce the misdiagnosis rate. Methods Fluorescent treponemal antibody absorption （FTAABS） test and treponema pallidum hemagglutination assay （TPHA） were applied to performing serologic examination according to the diagnostic criteria and analytic standard （see Venereal Disease Prevention and Cure Hand- book＂）. Results The syphilis-suffering rates of sex-active crowd （aged from 20 to 40） ,individual supply and marketing and service crew were 86.1% and 67.3 % ,respectively; the misdiagnosis rate was 23.1% ; the sources of infection were mainly sexual companions outside the marriage. Conclusion The high-risk group of syphilis infection is mainly made up of sex-active crowd, individual supply and marketing and service crew. The monitoring work should be strengthened. To avoid a higher misdiagnosis rate,the work of checking up suspicious patients in TPPA syphilis serology should be carried on initiatively. The sources of infection are mostly made up of sexual companions, which indicates it is necessary to constantly raise the supervising of society and effectively carry on health education intervention.