偏瘫患者骨质疏松症的危险因素

Risk Factors for Osteoporosis in Patients with Hemiplegia

目的分析影响偏瘫患者骨质疏松症发生的因素。方法采用双能X线骨密度仪测量366例康复期偏瘫患者全身骨密度,对骨质疏松症的危险因素进行单因素分析和多因素Logistic回归分析。结果共检出骨质疏松症患者56例(15.3%)。年龄≥60岁(OR=5.434,95% CI:2.734～10.801)、病程(OR=1.046,95% CI:1.013～1.080)、体重指数(OR=0.746,95% CI:0.622～0.840)、日常生活自理程度(OR=0.618,95% CI:0.444～0.858)是偏瘫患者发生骨质疏松症的独立危险因素。结论康复期偏瘫患者是骨质疏松症的高危人群,骨质疏松症发生的独立危险因素包括年龄≥60岁、低体重指数、病程长及日常生活自理程度低,对该类人群进行骨密度监测和骨质疏松症预防干预是十分必要的。

Objective To identify the risk factors for osteoporosis in patients with hemiplegia. Methods The total body bone mineral density （BMD） of 366 patients with hemiplegia in the stage of rehabilitation was measured with dual-energy X-ray absorptiometry. The data of the patients were analyzed with multiple logistic regressions. Results The incidence of osteoporosis was 15.3% （56/366） in the cohort. ≥60 years old （OR=5.434, 95% CI：2.734～10.801）, duration of disease （OR=1.046, 95% CI：1.013～1. 080）, body mass index （BMI） （OR=0. 746,95% CI：O. 622～0. 840）,ADL level （OR=0.618, 95% CI： 0.444～0. 858） were independently correlated with osteoporosis in patients with hemiplegia. Conclusion Patients with hemiplegia in the stage of rehabilitation were at a high risk of osteoporosis. Aged over 60 years old, lower BMI, longer duration of disease and ADL level were independent risk factors for osteoporosis, which called for supervision and prophylaxis on osteoporosis.