那如-3巴布剂质量标准研究

Study on Quality Standard of Naru-3 Cataplasm

目的建立那如-3巴布剂的质量标准。方法用紫外-可见分光光度法鉴别处方中草乌的主要成分,采用高效液相色谱法测定新乌头碱的含量。结果新乌头碱在0.1295～2.0740μg范围内线性关系良好,加样回收率为99.57%,RSD=1.28%。结论那如-3巴布剂定性、定量方法能有效控制该制剂的质量。

Objective To establish the quality standard of Naru-3 Cataplasm. Method The contents of Radix aconiti kusnezoffii were determined by UV-vis, and meaconitine was determined by HPLC. Results The linear range of meaconitine was 0.129 5-2.074 0 μg. The quality standard of Naru-3 Cataplasm was established. Conclusion The method can be used for quality control of Naru-3 Cataplasm.