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结直肠癌患者血浆K-ras基因突变情况分析 被引量:1

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摘要 采用直接测序法检测42例结直肠癌患者血浆、肿瘤组织及20例正常人血浆中K-ras基因突变情况。结果42例结直肠癌患者血浆K-ras基因突变17例(40.48%),肿瘤组织K-ras基因突变19例(45.24%)。对照组无血浆K-ras基因突变。认为K-ras基因突变发生于结直肠癌早期。检测血浆K-ras基因突变可作为结直肠癌的辅助诊断方法。
出处 《山东医药》 CAS 北大核心 2008年第30期76-77,共2页 Shandong Medical Journal
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