双源CT诊断冠心病和指导危险分层的价值

Value of dual-source CT in diagnosis and risk stratification of coronary artery disease

目的评估双源CT(DSCT)对冠心病的诊断以及指导危险分层的价值。方法50例临床诊断或疑诊为冠心病患者,先期接受DSCT检查后于1个月内行有创冠状动脉造影(CAG)检查。以CAG诊断为标准,分别评估DSCT诊断冠状动脉<50%、≥50%和≥75%狭窄性病变的敏感性、特异性、阳性预测值和阴性预测值。采用SPSS 13.0统计软件对两种检查结果做Spearm an等级相关检验。结果CAG显示冠状动脉为637段,DSCT可评估的冠状动脉为615段(96.5%)。DSCT对诊断<50%、≥50%和≥75%狭窄的敏感度分别为75.6%、83.2%和91.7%,特异度为97.6%、99.2%和99.8%。DSCT和CAG结果显著相关(P<0.01)。结论DSCT对于冠脉狭窄病变诊断的结果与CAG有高度一致性。

Objective To evaluate the value of dual-source CT （DSCT） in diagnosis and risk stratification of coronary artery disease （CAD） by taking conventional coronary angiography （CAG） as the references. Methods 50 established or consecutive CAD patients were examined, who received DSCT scan then CAG within 1 month. The sensitivity, specificity, positive predictive value and negative predictive value were calculated. Spearman＇ s test was used to prove the statistic significance. Results DSCT could evaluate 615 in 637 segments CAG evaluated and the evaluating rate was 96.5%. The sensitivity were75.6%, 83.2%, 91.7% respectively for detecting stenosis 〈50%, ≥50% and ≥75% and the specificity were 97.6% , 99.2% and 99.8%. There was significant correlation between DSCT and CAG to detect coronary stenosis. Conclusion The results of DSCT have high accordance with CAG in detecting coronary stenosis.