C反应蛋白在胰岛素抵抗及2型糖尿病中的意义

The Meaning of C-reactive Protein(CRP) in Insulin Resistance(IR) Type and 2 Diabetes Mellitus(T_2DM)

目的:观察血清C反应蛋白(CRP)与胰岛素抵抗(IR)以及2型糖尿病(T_2DM)的关系。方法:T_2DM患者76例,分为2组:T_2DM非IR组(DM1组)36例,T_2DM伴IR组(DM_2组)40例,并选择正常对照组(NC组)30例,分别测定CRP。结果:T_2DM1、T_2DM_2组的血清CRP水平均明显高于NC组,DM_2组的血清CRP水平有显著性增高(P<0.05)。结论:CRP介导的炎性反应与T_2DM的IR代谢综合征密切相关。

Objective：To observe the relation between C-reactive protein （CRP）and insulin resistance（IR）type 2 diabetes mellitus （T2DM）.Method：CRP was measured respectively in the T2DM patients with IR （n=36）,non IR （n=40）and healty control group.Result：CRP with T2DM patients was higher than health people,which CRP with T2DM IR patients was signifcantly increased.Conclusion：Inflammatory reaction mediated by CRP correlate IR metabolic syndrome with T2DM.