颅内动脉瘤的自然史

Natural History of Intracranial Aneurysms

颅内动脉瘤是一种严重的脑血管疾病。普通人群中的发病率在2％～4％之间。颅内动脉瘤的患病率随着人口老龄化和影像学技术的发展而逐年增高。动脉瘤自然病程的研究对于神经外科医师评价治疗措施的有效性具有重要意义。发生过蛛网膜下腔出血的动脉瘤患者与未发生过蛛网膜下腔出血的动脉瘤患者在自然病程上有着显著差异。颅内动脉瘤的年破裂率在0．066％～2％之间。影响动脉瘤破裂的危险因素包括动脉瘤的大小、生长部位、是否为多发性、生长速度，以及症状和患者的自身因素，如年龄、性别、高血压史和吸烟史等。

Intracranial aneurysms are a severe cerebrovascular disease. Its incidences ranged from 2% to 4% in general population. With the population aging and the development of imaging technique, the prevalence of intracranial aneurysm is increasing year by year. The research of natural course of aneurysm has important significance for neurosurgeons to evaluate the validity of therapeutic measures. There are significant differences between the patients with aneurysm who have had subarachnoid hemorrhage and those who have not. The rates of ruptured intracranial aneurysms per year ranged from 0. 066% to 2%. The risk factors that affect ruptured intracranial aneurysms including the size and place of aneurysm, whether it is multiple aneurysms or not, growth rate, and self-factors of patients, such as age, sex, and history of hypertension and smoking, etc.