甲亢患者尿β_2微球蛋白、白蛋白和IgG水平的检测

Levels Alterations of Urinary β 2-Microglobulin,Albulin and IgG in Patients with Hyperthyroidism

采用放射免疫分析法测定了７１例甲亢患者尿β２微球蛋白（β２－Ｍ）、白蛋白（ＡＬｂ）和ＩｇＧ水平，以观察甲亢患者肾脏功能的变化。结果表明甲亢患者尿β２－Ｍ、ＡＬｂ和ＩｇＧ水平明显高于正常对照组，肾脏损害检出率６７．６％，肾小球或肾小管同时受损率为２６．８％。

To observe renal function status in hyperthyroidism, urinary β 2-microglobulin(β 2-M),albulin (Alb) and IgG were measeured using radioimmunoassay in 71 patients with hyperthyroidism and 37 healthy as controls.urinary β 2-M, Alb and IgG were significantly higher in hyperthyroidism than that in the control group. It was found that impairment of renal functon appeared in 67.6% of patients with hyperthyroidism. Damage of glomerular and renal tubular function of hyperthyroidic patients were found in 63.4% and 31.0% respectively. These results suggested that abnormal renal function appeared in patients with hyperthyroidism.