摘要
应用增殖细胞核抗原(PCNA)单克隆抗体PC10免疫组化法,DNA含量及细胞核形态图像分析法,对58例鼻咽癌进行检测。结果显示,三种方法的检测结果具有较好的一致性,其中肿瘤细胞的DNA指数和DNA倍体分布最具有价值。结果表明,检测肿瘤细胞增殖活性对于判断鼻咽癌恶性变及估计患者的预后具有重要意义。
Cellular proliferation indices, the proliferating cell nuclear antigen (PCNA), DNA content index and mitotic figure counts (MFC) were evaluated in 58 cases of nasopharyngeal squamous cell carcinoma. The results suggested that DNA index of tumor cells and distribution of DNA were of great value to assess cellular proliferative activity of nasopharyngeal carcinoma. Three different cellular proliferative paramenters could be used as the predictor of tumor malignancy and prognosis.
出处
《耳鼻咽喉(头颈外科)》
1997年第4期220-223,共4页
Chinese Arch Otolaryngology-Head Neck Surg