参芎葡萄糖注射液治疗慢性肾衰竭临床观察

Observation on treatment of chronic renal failure with Shenqiong Glucose Injection

目的观察参芎葡萄糖注射液治疗慢性肾衰竭的疗效。方法将入选的50例患者随机分为对照组和参芎葡萄糖注射液治疗组,于3周后分别进行血肌酐(Scr)、尿蛋白(UP)、血脂(CH、TG、LDL-C、HDL-C)、红细胞压积(Hct)和纤维蛋白原(Fig)相关指标检测。结果治疗组治疗3周后Scr、UP、TG、HDL-C、Hct和Fig较治疗前明显改善(P<0.05),且Scr、HDL-C、Hct和Fig较对照组治疗后明显改善(P<0.05)。结论参芎葡萄糖注射液可改善慢性肾衰竭患者的肾功能,降低蛋白尿、血脂和血液黏稠度,延缓慢性肾衰竭的进展。

Objective To observe the curative effect of Shenqiong Glucose Injection on chronic renal failure. Method All 50 patients with chronic renal failure were randomly divided into the control group and treatment group treated with Shenqiong Glucose Injection. The indexes of serum creatinine （Scr）, urine protein （UP）, blood lipid including cholesterol （CH）, triglyceride （TG）, low-density lipoprotein cholesterol （LDL-C） and high-density lipoprotein cholesterol （HDL-C）, hematocrit （klct） and fibrinogen （Fig） were detected after 3 weeks. Result In the treatment group the indexes of Scr, UP, TG, HDL-C, Hct and Fig had better outcomes 3 weeks after the treatment than those before the treatment （P〈0.05）. The indexes of Scr, HDL-C, Hct and Fig were improved in the treatment group than those in the control group after the treatment （P〈0.05）. Conclusion Shenqiong Glucose Injection can improve the renal function, decrease the levels of proteinuria, blood lipid and blood viscosity, and stay the development of chronic renal failure.