血小板体积及分布宽度与老年病血瘀证关系的临床研究

Clinical Study on Relationship of MPV,PDW and Blood Stasis Syndrome

对２５６例老年病患者根据血瘀证诊断标准分属血瘀证和非血瘀证两组，同时设４０例健康体检者作为对照组，进行血小板计数（ＰＬＴ）、平均体积（ＭＰＶ）及分布宽度（ＰＤＷ）的测定．结果发现ＭＰＶ和ＰＤＷ在老年病组明显高于对照组，在血瘀证组明显高于非血瘀证组和对照组，差异均有显著性意义（Ｐ＜０．０５或０．０１），提示中医理论“老年多瘀”有其科学性，老年病血瘀证存在着ＭＰＶ和ＰＤＷ异常变化，为临床诊断此证提供微观参考指标．

Two hundred fifty six cases of senile diseases were divided into two groups:group I blood stasis,group Ⅱ non-blood stasis;together with 40 healthy people as control group.PLT、MPV and PDW were measured for each person.The results showed that MPV and PDW of senile disease group were higher than that of control group,and that of graup Ⅰ were higher than that of group Ⅱ and also that of control group (P<0.05 or 0.01).It was suggested that 1) TCM theory more stasis symdrome in senile disease,has its scientific base;2) the abnormal changes of MPV and PDW may be one of the pathophysiological bases of blood stasis syndrome in senile diseases;3) the abnormal changes of MPV and PDW would provide micro-index for blood stasis syndrome in senile diseases.