立其丁加普鲁卡因封闭治疗局部组织缺血坏死的疗效观察和护理

Curative effect observation of local blockage with phentolamine plus procaine in treating ischemic necrosis

目的观察立其丁加普鲁卡因封闭对治疗局部组织缺血坏死的疗效及总结护理要点。方法对7例因药物外渗及无创辅助通气面罩压迫致局部组织缺血的部位,采用立其丁加0.5%普鲁卡因局部封闭治疗。结果本组1例局部封闭3次后,组织恢复供血,皮肤温暖;6例局部封闭6～8次后,其中5例局部组织恢复供血,皮肤温暖,另1例因坏死组织的范围较大,缺血坏死较严重的皮肤中央部位的组织发生脱落,但无出现感染。治疗有效率为85.7%,无效为14.3%。结论采用局部封闭治疗,可改善因药物外渗及无创辅助通气面罩压迫而造成的局部缺血、坏死组织处的血运情况,同时可减轻患者的痛苦。

Objective To observe the effectiveness of local blockage with phentolamine plus procaine in treating ischemic necrosis. Method Seven patients with ischemic necrosis, which was caused by drug extravasation and pressure of non-invasive ventilation face mask, were treated by local blockage with phentolamine plus procaine. Results After three times of local blockage, blood supply was restored and skin became warm in one patient. After 6 - 8 times of local blockage, blood supply was restored and skin became warm in five patients, and the tissue in the central part of skin with severe ischemic necrosis shed off in one patient, but no infection occurred. The effective rate was 85.7%, and the ineffective rate was 14.3%. Conclusion For ischemie necrosis caused by drug extravasation and pressure of non-invasive ventilation face mask, local blockage with phentolamine plus procaine is effective in improving blood supply in the sites of ischemic necrosis and relieve patients＇ pain.