间接性颞下颌关节损伤组织学研究

The Effect of Indirect Trauma on the Goat Temporomadibular Joint: A Histopathologic Study

通过自身对照的方法，用自制撞击装置撞击２０只山羊右侧下颌骨体部，造成右侧颞下颌关节间接性损伤，伤后２ｈ、１月、３月和６月处死动物，光镜观察颞下颌关节改变。结果发现：颞下颌关节间接性损伤后，出现关节滑膜及关节盘撕裂，关节腔内血肿形成。３月后关节表面凹凸不平，骨质严重侵蚀，并出现骨赘及骨质硬化；关节盘厚薄不一，玻璃样变。这些病变和骨关节病发展过程中的病理变化完全相似。

The aim of this experiment was to study the effect of indirect trauma on the goat temporomadibular joint (TMJ). Trauma to the TMJ was achieved through an impact to the right mandibular angles of 20 goats, their left TMJs were used as a contrals. The animals were killed after 2h, 1 month, 3 months and 6 months. Light microscopic observations revealed that the condyles exhibited an eburnated, eroded surface with osteophytes, the disks were thinned or perforated, and the temporal surfaces were thinkened and the lining were separated. These changes were histologically similar to those of the advanced osteoarthritis. This study suggests that the indirect trauma on TMJ lead to osteoarthritis.