脊髓细胞移植支架的理论研究进展

Progress in the scaffolds for spinal cell transplantation

神经组织工程技术的发展在脊髓损伤后神经功能恢复的研究方面取得了较大的进步。细胞支架做为神经组织工程的重要部分,按材料可分为天然生物支架材料、人工合成支架材料和复合型支架材料3大类。此外,纳米技术也开始在支架材料中得到应用并取得初步成效。目前细胞支架在应用方面还存在许多问题,需进一步研究和改进。随着生物学技术和其它相关技术的发展,细胞移植支架在脊髓损伤修复中将发挥更大的作用。

A great progress has been achieved in research on repair of nerve functional recovery following spinal cord injury because of the development of nerve tissue engineering. As an important part of nerve tissue engineering, cell scaffold is divided into natural biomaterials, synthetic materials and composite materials. Besides, nanotechnology has been applied to study scaffolds. However, there are many problems in the application of cell scaffold and further study is needed. With the continued development of biotechnique and cross-correlated technique, the cell transplantation scaffold will make more effect on repair of spinal cord injury.