糖尿病合并尿路感染患者临床特点分析及三金片的治疗作用

Clinical Features of Diabetes Mellitus Associated with Urinary Tract Infection and the Therapeutic Effect of Sanjin Tablet

目的:分析糖尿病合并尿路感染患者临床特点,并评判三金片的治疗效果。方法:记录86例糖尿病合并尿路感染患者临床症状特点及洁尿培养的病原菌,进行综合分析,并将该86例患者随机分为两组,对照组根据药敏给予抗生素治疗(药敏结果未出来前给左氧氟沙星),治疗组在对照组的基础上加用三金片,观察两组的临床疗效及细菌学疗效。结果:临床症状特点以无症状菌尿及尿急、尿频为多见,病原菌以大肠埃希菌检出率最多(54.7%);治疗组临床疗效及细菌学疗效均优于对照组。结论:糖尿病患者应将尿常规作为常规检验,以排查尿路感染,尤其是无症状菌尿;在抗生素治疗的基础上加用三金片,对糖尿病合并尿路感染患者疗效显著。

OBJECTIVE： To analyze the clinical features of diabetes mellitus associated with urinary tract infection and evaluate the therapeutic effect of Sanjing tablet on this disease. METHODS ： The clinical features and the pathogenic bacteria detected in urine culture of 86 patients with diabetes mellitus associated with urinary tract infection were recorded for a meta- analysis. The 86 cases were randomly assigned to receive antibiotic therapy （levofloxacin was used before obtaining of drug susceptibility results） alone （control group） or in combination with Sanjing tablet （trial group）. The clinical efficacy and bacteriological therapeutic effect in the two groups were evaluated. RESULTS： The diabetes mellitus associated with urinary tract infection was characterized by asymptomatic bacteriuria, urgent micturition and frequent micturiton. Escherichia Coli strains represented the majority of the isolated pathogenic bacteria, accounting for 54.7 %. The trial group was superior to control group in both clinical efficacy and bacteriological therapeutic effect. CONCLUSION： Urine routine test should be conducted routinely for patients with diabetes mellitus to exclude the possibility of urinary tract infection in particular the asymptomatic bacteriuria. Antibiotic therapy in combination with Sanjin tablet showed remarkable efficacy for patients with diabetes meIiitus associated with urinary tract infection.