液基细胞学（TCT）病变（CIN）筛查子宫颈癌前的重要性

The significance of TCT Screening for CIN

了解液基细胞学筛查子宫颈癌前病变的敏感性、特异性、准确性，以便早期发现和处理宫颈癌前病变，降低子宫颈癌发病率。方法：本组收集2008年1月30日至5月30日妇科患者200例，患者同时行宫颈TCT和组织活检。①特制细胞采集刷，宫颈取材，细胞液保存，上机搅拌、离心、分层，95％酒精固定、巴氏染色、封片、阅片。②子宫颈转化带多点活检、石蜡包埋切片、苏木精—伊红染色、光镜观察。按诊断性试验评价四格表统计分析。结果：子宫颈液基细胞学检测LSIL敏感性、特异性、准确性分别为90．0％、96．8％、96．5％；HSIL敏感性、特异性、准确性分别为84．6％、95．3％、95．0％。结论：液基细胞学敏感性、特异性、准确性高，是目前筛查子宫颈癌前病变的可靠手段。

Objective： To determine the significance of TCT screening for CIN. Methods： 200 cases are examined with TCT and biopsy at the same time from Jan. 30, 2008, to May. 30, 2008. ①Cewical cells are collected by a special cell brush. These collected cells are put into a small bottle containing cell liquid. Then the cells, having been processed and dyed with Bashi liquid, are observed under a microscope. ②Multiple biopsies are performed at the transform zone of cervix. The sections of cervical tissue are made, dyed with Surnujing- yihong and then observed under a microscope. The results of biopsy and TCT are analyzed with statistics. Results： The sencitivity, specificity and accuracy of TCT screening-for LSIL are 90. 0%, 96. 8% and 96. 5% respectively, and those for HSILare 84. 6%, 95. 3% and 95. 0% respectively. Conclusions： TCT screening is a good method to discover CIN early.