丹红注射液治疗缺血性脑卒中的疗效观察

Clinical Observation of Danhong Injection in Treating Ischemic Cerebral Stroke

目的观察丹红注射液治疗缺血性脑卒中的临床疗效。方法缺血性脑卒中患者198例,随机分为治疗组和对照组,各99例。治疗组用丹红注射液30ml,静脉滴注,1次/d;对照组用香丹注射液20ml,静脉滴注,1次/d。观察并比较两组血液流变学参数、临床疗效和神经功能缺损改善情况。结果治疗组治疗前后血液流变学参数和神经功能缺损均有非常明显改善,(P<0.01);治疗组总有效率及治疗后血液流变学变化与对照组比较,差异有统计学意义(P<0.01)。结论丹红注射液可明显改善缺血性脑卒中患者的血液流变学参数和神经功能缺损,丹红注射液治疗缺血性脑卒中有效,且疗效优于香丹注射液。

Objective To explore the clinical curative effect of Danhong injection intreating ischemic cerebral stroke. Methods 198 cases of ischemic cerebral stroke were randomly divided into the treatment group（99cases） and the contrast group（99cases）. The treatment group was treated by danhong injection （30 ml） with mainline one time each day. The contrast group was treated by xiangdan injection（20 ml） with mainline one time each day. The clinical curative effect, trauma score of nerve function and change of hemorheology were observed between the two groups. Results The parameter of hemorheology and trauma of nerve function were obviously improved （ P 〈 0.01 ）. The total effectrate and improvement of hemorheology in the treatment group has a significant difference compared with those in the contrast group （P 〈 0.01 ）. Conclusion Danhong injection can improve the parameter of hemorheology and trauma of nerve function of ischemic cerebral stroke obviously. Danhong injection was proved to be effective intreating isehemie cerebral stroke, and it is superior to xiangdan injection in curative efficacy.