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瑞芬太尼和丙泊酚用于老年患者开胸手术麻醉的临床观察 被引量:2

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摘要 目的评价瑞芬太尼复合丙泊酚用于老年开胸手术患者麻醉的可行性和有效性。方法择期行开胸手术的老年患者54例,随机分为两组,每组27例,两组性别、年龄、体质量均无差异,麻醉诱导R组采用瑞芬太尼0.5μg/kg、咪达唑仑0.05mg/kg、丙泊酚1~2mg/kg、维库溴铵0.08mg/kg,气管插管后微量泵持续输注瑞芬太尼0.2μg/kg.min、丙泊酚2mg/kg.h、维库溴铵60~80μg/kg.min;F组诱导以芬太尼2~3μg/kg、咪达唑仑0.05mg/kg、丙泊酚1~2mg/kg、维库溴铵0.08mg/kg,插管后微量泵持续输注芬太尼0.2μg/kg.min、丙泊酚2mg/kg.h、维库溴铵60~80μg/kg.min以维持麻醉。观察两组对MAP、HR、自主呼吸恢复时间、苏醒时间、拔管时间的影响及恶心、呕吐等不良反应。结果麻醉诱导后两组MAP、HR均较诱导前有所下降,P<0.05,两组间无明显差异。自主呼吸恢复时间、苏醒时间、拔管时间F组均明显高于R组,P<0.01,恶心、呕吐不良反应两组差异不明显。结论瑞芬太尼复合丙泊酚用于老年患者开胸手术的麻醉诱导和维持是可行的和有效的,具有一定的临床推广价值。
作者 郝雪峰
出处 《中国实用医药》 2008年第33期139-140,共2页 China Practical Medicine
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