磷钨酸/硅胶催化剂催化合成丁酮1,2-丙二醇缩酮

Catalytic Synthesis of Butanone 1,2-Propanediol Ketal over Phosphotungstic Acid/Silica

以溶胶-凝胶法制备磷钨酸/硅胶催化剂,通过丁酮和1,2-丙二醇反应合成丁酮1,2-丙二醇缩酮,探讨了磷钨酸/硅胶对缩酮反应的催化活性,较系统地研究了酮醇摩尔比、催化剂用量、反应时间和带水剂用量诸因素对产品收率的影响。实验表明,磷钨酸/硅胶是合成丁酮1,2-丙二醇缩酮的良好催化剂,在 n(酮):n(醇)=1:1.4,催化剂用量为反应物料总质量的0.75%,环己烷为带水剂,反应时间60 min 的优化条件下,丁酮1,2-丙二醇缩酮的收率可达80.0%。

Butanone 1,2 -propanediol ketal was synthesized from butanone and 1,2 -propanediol in the presence of phosphotungstic acid/silica prepared by sol - gel method. The factors influencing the synthesis were discussed and the best conditions were found out. The optimum conditions were as follows：molar ratio of butanone to 1,2 -propanediol 1： 1.4,the quantity of catalyst equal to 0.75% of feed stocks,the dewatering reagent cyclohexane 10 mL,and the reaction time 60 min. Phosphotungstic acid/silica was an excellent catalyst for synthesizing butanone 1,2 - propanediol ketal and its yield could reach over 80.0%.