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血浆D-二聚体与溃疡性结肠炎病情转归相关性的探讨 被引量:6

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摘要 目的:探讨D-dimer与UC病情活动性是否存在相关性。方法:UC活动期患者127例作为研究对象,对照组53例,所有研究对象于治疗前及疗程结束后采静脉血3ml并分离血浆。以免疫比浊法检测血清D-二聚体。结果:活动期UC患者血D-dimer明显高于对照组。抗凝治疗组经治疗后临床活动性评分优于未经抗凝治疗组,经抗凝治疗后患者D-dimer明显低于未经抗凝治疗组。结论:D-dimer血浆浓度与活动性UC患者的病情分级呈正相关。活动性UC患者处于明显的血栓前状态,适量应用低分子肝素以改善患者血液高凝状态对活动性溃疡性结肠炎治疗有效。
出处 《吉林医学》 CAS 2008年第23期2219-2220,共2页 Jilin Medical Journal
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