距离震源远近与抗震救灾医护人员肝肾功能相关性研究

The correlation study on the function of liver and kidney with the intensity of stress

目的:探究不同环境地域对抗震救灾医护人员肝肾功能的影响。方法:将赴汶川地震不同区域的某部抗震救灾医护人员按距离震源远近依次分为A(成都)、B(都江堰)和C(水磨)三组(救灾时应激强度A<B<C)。D组为非灾区健康人员对照组。检测肝肾功能生化指标,并将检验结果进行统计分析。结果:反映肝功能生化指标ALT、AST、CK、TP、GLU均随距震源由远及近呈增加趋势(D<A<B<C),与对照组相比差异有显著统计学意义(P<0.05);A、B、C三组间ALT、AST、CK差异有统计学意义(P<0.05),TP、GLU无统计学差异(P>0.05)。反映肾脏功能生化指标Urea、UA、Cr均随距震源由远及近而增加(D<A<B<C),与对照组相比差异有统计学意义(P<0.05);A、B、C三组间Urea、UA差异有统计学意义(P<0.05),Cr未见显著统计学差异(P>0.05)。结论:距离震源越近所受到的应激强度越强,较强程度的应激可引起肝、肾等脏器代谢紊乱,在重大应激事件时应注意对这些脏器的防护。

Objective： To study the effect of different areas from seismic origin on liver and kidney function changes of medical rescue team members in Wenchuan earthquake.Methods： According to the distance to seimic origin from far to near,the medical team was divided into 3 groups,which were named as A（Chengdu）,B（Dujiangyan） and C（Shuimo）,D was control group（healthy volunteers）.The blood samples were examined,statistically analysis were employed with the results.Results： ALT,AST and CK of group A,B,C were higher than that of group D（D0.05）;Urea and UA of group A,B,C were higher than that of group D（D0.05）.Conclusion： Intensity of stress would become stronger as distance to seimic origin changed from far to near.Abnormal metabolish of liver and kidney function were found and it is necessary to prevent these organs from injury of stress.