单区与多区切削治疗高度近视远期效果观察

Comparison of long-term efficacy between S-LASIK and M-LASIK for high myopia

目的比较单区和多区切削准分子激光原位角膜磨镶术(LASIK)矫治高度近视在安全性、有效性、预测性和稳定性方面的远期效果。方法40例(78眼)角膜薄的高度近视患者分为单区切削治疗组(A组)和多区切削治疗组(B组),分别行单区切削和多区切削LASIK矫治,随诊5年以上,分析比较术前和术后角膜厚度、屈光度、裸眼视力、最佳矫正视力的变化以及术后并发症发生情况。结果术后5年两组裸眼视力显著提高,屈光度和角膜厚度显著降低(P<0.01),两组之间术后裸眼视力、最佳矫正视力、屈光度差异无显著性(P>0.05),术后剩余角膜厚度差异有高度显著性(P<0.01)。结论单区切削与多区切削LASIK手术有效性、预测性、稳定性、安全性差异无显著性;在节省角膜组织方面,多区切削比单区切削更有优势。

Objectlive To compare of the safety, effectiveness, predictability and stability of single optical zone （S- LASIK） and multi - optical zone （M - LASIK）- laser in situ keratomileusis （LASIK） for treatment of high myopia.Methods.78 eyes of 40 cases with high myopia and thin corneas were divided into single - zone group （group A） and multi-zone group （group B）. The patients received S- LASIK and M- LASIK treatment with a 60 - month follow - up. Preoperative and postoperative corneal thickness, refraction, uncorrected visual acuity, best corrected visual acuity changes and complications were analyzed.Results Both groups had better uncorrected visual acuity, decreased refraction and corneal thickness 60 months after operation （ P 〈 0.01）. There were no significant differences in uncorrected visual acuity, best corrected visual acuity, refraction between the two groups （ P 〉0.05）,but there was significant difference in the residual corneal thickness （ P 〈 0. 01）.Conclusion There was no sig-nifieant difference in efficacy, predictability, stability and safety between single- zone and multi - zone LASIK for patients with thin cornea high myopia, while in saving cornea tissues, the multi - zone LASIK is superior to single - zone LASIK.