摘要
目的:研究产自长白山地区的长白瑞香(Daphne koreana)的化学成分。方法:应用硅胶柱色谱,Sephadex LH-20和RP-18反相柱色谱的方法分离和纯化化合物,通过光谱方法及理化性质鉴定化合物结构。结果:从长白瑞香氯仿部位分离得到10个化合物,分别为:双白瑞香苷(1),7-甲氧基-木犀草素-5-O-β-D-葡萄糖苷(2),樱花苷(3),芫花苷(4),瑞香新素(5),异瑞香新素(6),5-去甲氧基瑞香新素(7),紫丁香苷(8),左旋松脂酚(9),左旋松脂酚-4-O-β-D-葡萄糖苷(10)。结论:所有化合物均为首次从该植物中分得。
AIM: To study the chemical constituents of the stems and barks of Daphne koreana from the hangbai Mountain in the North of China. METHODS: Compounds were separated by column chromatography with silica gel, Sephadex LH-20 and RP-18 silica gel. Their structures were elucidated on the basis of physiochemical and spectral analyses. RESULTS: Ten compounds were isolated from D. koreana and the structures were identified as daphnoretin-7-O-β-D-glucopyranoside (1), luteolin-7-methylether-5-O-β-D-glucopyranoside (2), sakuranin (3), yuankanin (4), daphneticin (5), isodaphneticin (6), 5′-demethoxydaphneticin (7), syringin (8), (-)-pinoresinol (9) and (-)-pinoresinol- 4-O-β-D-glucopyranoside (10). CONCLUSION': Compounds 1 - 10 were isolated from this plant for the first time.
出处
《中国天然药物》
SCIE
CAS
CSCD
2008年第6期411-414,共4页
基金
supported by the Science and Technology Commission Foundation of Shanghai (No.05DZ19 733)~~
关键词
长白瑞香
瑞香科
化学成分
Daphne koreana
Thymelaeaceae
Chemical constituents