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右旋糖酐70替代血制品治疗肝硬化张力性腹水的疗效观察

Evaluation on the Effect of Substitute Dextran 70 for Blood Products in Liver Cirrhosis with Tense Ascitic
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摘要 目的:探讨用右旋糖酐-70加营养支持替代血制品对肝硬化张力性腹水的疗效。方法:将肝硬化张力必腹水的住院病人按Detskey's标准进行营养状况评估后给予相应的营养支持,随机分为两组,组-Ⅰ腹腔穿刺放腹水加静脉滴注右旋糖酐-70加补充复方氨基酸;组-Ⅱ腹腔穿刺放液加静脉滴注白蛋白或血浆,疗程2周,每周测量1次腹围、体重及检测白蛋白、总蛋白、血肌酐、血尿素氮、血清电解质(钾、钠、氯等离子)变化。结果:两组病人的腹围、体重、白蛋白、总蛋白、血肌酐、血尿素氮、血清电解质(钾、钠、氯)在统计学上无明显差异。结论:右旋糖酐-70加补充复方氨基酸能够替代人血制品治疗肝硬化张力性腹水。 Objective: To investigate the curative effect of substitute Dextran 70 plus nutritional support for blood products in liver cirrhosis with tense ascitic. Methods: Hospitalized patients with tense ascitic were evaluated in nutritional status using Detskey's standard and given propotional nutritional support, then randomly divided into two groups: group one: abdominal paracentesis plus intravenous infusion dextran-70 and supply amino acid; group two: abdominal paracentesis plus intravenous infusion albumin or plasm. Time of therapy is two weeks. Measuring abdomen circumference, and body weight, and detecting serum albumin, serum total protein, serum creatinine, serum dielectric(potassium ion, sodium ion, chlorine ion, etc), once a week. Results: Abdomen circumference, body weight, serum albumin, serum total protein, serum creatinine, and serum dielectric (potassium, sodium and chlorine) had no statistically significant difference in both groups. Conclusion: Dextran 70 supply amino acid can substitute blood products to treat liver cirrhosis with tense ascitic.
出处 《抗感染药学》 2008年第4期247-250,共4页 Anti-infection Pharmacy
关键词 右旋糖酐-70 血液制品 肝硬化 张力性腹水 dextran 70 blood products cirrhosis tense ascitic
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