糖尿病母亲的婴儿随访及家系调查

A Study of the Genealogical and Follow-up Investigation in IDMs

为观察糖尿病母亲的婴儿(IDMS)生长发有状况及探讨IDMs与糖尿病的相关性.方法对33例IDMs进行定期体格发育随访和智商(IQ)测定及家系调查.结果(1)体格发育及IQ处于正常范围;(2)检出糖尿病患儿(女,9.9岁)1例,患病率为3.03%;(3)31个家系中糖尿病家族史阳性家系21个,占66.7% 结论 IDMs糖尿病患病风险高于群体,其遗传背景与糖尿病患儿显示一致性.强调对IDMs远期随访及优育宣教尤其是多代连续造传的家系,有益于IDMs的健康成长及防治糖尿病.

To study on the development state of infants with diabetic mothers (IDMs) and the heriditary correlation between IDMs and diabetes mellitus (DM). Methods Follow-up of 33 IDMs cases, their intelligent quotient (IQ) and genealogical investigations were studied . Results (1) The physical development and IQ were in normal range?2)One 9-year-old DM girl was found in this series with an incidence of 3. 03%;(3) The positive genealogical findinge of DM were in 21 of 31 families (67. 7%). Conclusions The incidence risk of DM in IDM was higher than that of normal population a genetic background correlated with the occurence of DM in IDM a longterm follow-up study and eugenic education should be emphasized.