炎症性肠病与脂肪酸

Inflammatory Bowel Disease and Fatty Acid

近年炎症性肠病(IBD)的发病率呈上升趋势。随着对IBD发病机制的逐步深入了解,许多新的研究结果显示一些脂肪酸,如短链脂肪酸和ω-3多不饱和脂肪酸,在IBD的治疗中具有独特优势和应用前景,可作为新的辅助治疗手段。本文就近年来用于治疗IBD的脂肪酸的作用机制和临床疗效作一综述。

The incidence of inflammatory bowel disease （IBD） has been increasing in recent years. With a deeper understanding of the pathogenesis of IBD, many new findings in research studies suggest that some fatty acids such as short chain fatty acids and ω-3 polyunsaturated fatty acids show distinct advantage and perspective in the treatment of IBD. The use of these fatty acids may become a new adjunctive therapy. The mechanism and therapeutic effects of fatty acids in the treatment of IBD were reviewed in this article.