间充质干细胞在风湿性疾病修复治疗中的研究进展
摘要
在风湿性疾病中，关节损伤和修复之间的平衡决定了关节炎的结局，修复过程失败就会导致关节破坏以及最终的功能残疾。因此，组织修复成为一个重要的治疗目标。关节的生物学修复是以细胞为基础的。间充质干细胞（mesenchymal stem cells，MSCs）是一类具有自我复制、多向分化潜能的多能干细胞，近年研究还发现其具有免疫调节作用。
出处
《中华风湿病学杂志》
CAS
CSCD
2008年第12期847-850,共4页
Chinese Journal of Rheumatology
参考文献28
-
1Adams GB, Scadden DT. The hematopoietic stem cell in its place. Nat Immunol, 2006, 7: 333-337.
-
2Suzawa M, Takada I, Yanagisawa J, et al. Cytokines suppress adipogenesis and PPAR-γ function through the TAK1/TAB1/NIK cascade. Nat Cell Biol, 2003, 5: 224-230.
-
3Lukic IK, Grcevic D, Kovacic N, et al. Alteration of newly induced endochondral bone formation in adult mice without tumour necrosis factor receptor 1. Clin Exp Immunol, 2005, 139: 236- 244.
-
4Jones EA, English A, Henshaw K, et al. Enumeration and phenotypic characterization of synovial fluid multipotential mesenchymal progenitor cells in inflammatory and degenerative arthritis. Arthritis Rheum, 2004, 50: 817-827.
-
5Marinova-Mutafchieva L, Williams RO, Funa K, et al. Inflammation is preceded by tumor necrosis factor-dependent infiltration of mesenchymal ceils in experimental arthritis. Arthritis Rheum, 2002, 46: 507-513.
-
6Li X, Makarov SS. An essential role of NF-κB in the tumor-like phenotype of arthritic synoviocytes. Proc Natl Acad Sci USA, 2006, 103: 17432-17437.
-
7Lories RJ, Derese I, Luyten FP. Modulation of bone morphogenetic protein signaling inhibits the onset and progression of ankylosing enthesitis. J Clin Invest, 2005, 115: 1571-1579.
-
8Murphy JM, Fink DJ, Hunziker EB, et al. Stem cell therapy in a caprine model of osteoarthritis. Arthritis Rheum, 2003, 48: 3464- 3474.
-
9Van Beuningen HM, Glansbeek HL, van der Kraan PM, et al. Differential effects of local application of BMP-2 or TGF-β1 on both articular cartilage composition and osteophyte formation. Osteoarthritis Cartilage, 1998, 6: 306-317.
-
10Murphy JM, Dixon K, Beck S, et al. Reduced chondrogenic and adipogenic activity of mesenchymal stem cells from patients with advanced osteoarthritis. Arthritis Rheum, 2002, 46: 704-713.
-
1姚青,宋治远.先天性冠状动脉瘘的介入治疗现状[J].心血管病学进展,2010,31(5):659-661. 被引量：26
-
2李玉明.心肌梗死后组织修复治疗的现状与展望[J].武警医学,2004,15(11):803-805.
-
3王琦,刘玉琴,杨素琴.胸腔闭式引流治疗自发性气胸的观察与护理[J].延安大学学报（医学科学版）,2005,3(4):68-68.
-
4姜维良,孙庆峰,张英男,孙占峰,马军,王海涛.右位主动脉弓伴Stanford B型主动脉夹层的腔内修复治疗1例报告[J].中国实用外科杂志,2006,26(10):791-792. 被引量：4
-
5朱水波,夏峰,朱健.主动脉弓降部腔内修复治疗的现状[J].中国循环杂志,2014,29(4):318-320. 被引量：4
-
6贾堂宏,张佐伦.细胞凋亡与关节破坏[J].山东医药,2002,42(17):68-69.
-
7张伟,吴本俨.细胞间粘附分子-1、肿瘤坏死因子-α在胃粘膜损伤中的作用[J].人民军医,2001,44(7):44-45.
-
8张圆圆,石琳.循环内皮细胞和内皮祖细胞与儿童原发性高血压关系的研究进展[J].国际儿科学杂志,2016,43(11):833-835. 被引量：3
-
9黄瑞,赵钢.血浆肝细胞生长因子和同型半胱氨酸与高血压病合并颈动脉粥样硬化的相关性[J].中国煤炭工业医学杂志,2012,15(1):28-30. 被引量：5
-
10李勇,徐建军,董啸,吴永兵.覆膜支架植入治疗主动脉夹层4例[J].江西医药,2007,42(8):695-696.
