3Enomoto A, Kimura H, Chairoungdua A, et al. Molecular identification of a renal urate anion exchanger that regulates blood urate levels [ J ]. Nature,2002,417:447 - 452.
4Ichida K, Hosoyamada M, Hisatome I, et al. Clinical and molecular analysis of patients with renal hypouricemia in Japan-influence of URAT1 gene on urinary urate excretion [ J]. J Am Soc Nephrol,2004,15 : 164 - 173.
5Oda M, Satta Y, Takenaka O, et al. Loss of urate oxidase activity in hominoids and its evolutionary implications [ J ]. Mol Biol Evol,2002,19:640 - 653.
6Lin KC, Lin HY, Chou P. The interaction between uric acid level and other risk factors on the development of gout among asymptomatic hyperuriccmic men in a prospective study[ J]. J Rheumatol,2000,27 : 1501 - 1505.
7Choi HK, Atkinson K, Karlson EW, et al. Purine - rich foods, dairy and protein intake, and the risk of gout in men[J]. N Engl J Med,2004,350:1093 - 1103.
8Choi HK,Atkinson K, Karlson EW, et al. Obesity, weight change, hypertension, diuretic use, and risk of gout in men: the Health Professionals Follow- up Study [ J ]. Arch Intern Med ,2005 ,165 :742 -748.
9Emmerson BT. Effect of oral fructose on urate production [ J ]. Ann Rheum Dis, 1974,33:276 - 280.
10Choi HK, Atkinson K,Karlson EW',et al. Alcohol intake and risk of incident gout in men: a prospective study [ J ]. Lancet,2004,363:1277 - 1281.
5Smith E, Hoy D, Cross M, et al.The global burden of gout : estimates from the Global Burden of Disease 2010 study [J] .Ann Rheum Dis,2014,73(8) : 1470-1 476.
6Hershfield MS. Reassessing serum urate targets in the management of refractory gout : can you go too low [ J ]. Curr Opin Rheumatol, 2009,21 (2) : 138-142.
