GC-MS法鉴别藿香正气丸中广藿香和厚朴

GC-MS Identification of Pogostemon cabin and Cortex Magnoliae Officinalis in Huoxiang Zhengqi Pills

目的:采用气相色谱-质谱联用(GC-MS)法鉴别藿香正气丸中的广藿香和厚朴。方法:采用超声萃取技术提取藿香正气丸的成分,色谱柱为SPB-1701石英毛细柱(30m×0.25mm×0.25μm),载气为He,离子源为EI源,电子能量为70eV。结果:可同时鉴别出来自广藿香的广藿香醇和来自厚朴的厚朴酚、和厚朴酚等主要成分。结论:该方法简便、迅速、准确、可靠,可用于藿香正气丸的质量控制。

OBJECTIVE： To identify Pogostemon cablin and Cortex Magnoliae Officinalis in Huoxiang zhengqi pills by Gas Chromatography- Mass Spectrometry. METHODS： Pogostemon cablin and Cortex Magnoliae Officinalis in Huoxiang zhengqi pills were extracted by ultrasound extraction technology and identified on SPB- 1701 column（30 m × 0.25 mm × 0.25 μm） with He as carrier gas and El as ion source at an electron energy of 70 eV. RESULT： The main components such as Patchouli alcohol from Pogosternon cablin, and Magnolol and Honokiol from Cortex Magnoliae Officinalis were identified simultaneouly. CONCLUSION： The method is simple, rapid, accurate and reliable, and applicable for the quality control of Huoxiang zhengqi pills.