含丹参、甘草、大黄的中成药与西药配伍的处方分析

Analysis of Prescriptions on the Compatibility of Chinese Patent Medicines Containing Salvia Miltiorrhiza,Radix et Rhizoma Glycyrrhizae and Radix et Rhizoma Rhei with Western Medicines

目的:促进临床中西药的合理配伍使用。方法:随机抽查北京大学第三医院2006年7月10日～2006年7月15日的门诊处方,按照处方中含丹参、甘草、大黄等成分的中药分别与西药进行配伍分析。结果:共审查24000张处方,其中有3213例患者有中西药配伍使用情况,共计6830张处方;有128例与含丹参成分中成药不合理配伍,118例与含甘草成分中药不合理配伍,16例与含大黄成分中药不合理配伍。结论:在处方中有中西药配伍时,应考虑二者理化性质及药性,做到合理配伍。

OBJECTIVE： To improve the rational compatible use of Chinese patent medicines with western medicines. METHODS： A total of 24 000 prescriptions were randomly sampled from July 10th to July 15th in 2006 for an analysis of the compatibility of Chinese patent medicines containing Salvia miltiorrhiza, Radix et Rhizoma Glycyrrhizae, Radix et Rhizoma Rhei with western medicines.RESULTS：Of the total 24 000 prescriptions analyzed, 6 830（or 3 213 patients） involved combined use of Chinese patent medicines with western medicines, of which, the irrational combination for Salvia miltiorrhiza -contained, Radix et Rhizoma Glycyrrbizae contained and Radix et Rhizoma Rhei-contained Chinese medicines with western medicines totalled 128, 118 and 16 cases respectively. CONCLUSION： When the Chinese patent medicines being used in com- bination with western medicines, their physicochemical and pharmacological properties should be taken into fully consideration so as to achieve rational combination.