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体部伽玛刀与手术治疗早期非小细胞肺癌的疗效比较

Body Gamma Knife Radiotherapy vs Surgery for Early-Stage Non-Small Cell Lung Cancer:Comparison of Efficacy
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摘要 目的评价体部伽玛刀治疗与手术治疗早期非小细胞肺癌的疗效,探讨合理的治疗模式。方法回顾性分析2000/2004年住院治疗的85例早期非小细胞肺癌病例,其中体部伽玛刀治疗组40例,手术治疗组45例,所有患者均接受辅助化疗4周期。结果体部伽玛刀治疗组1、2、3年生存率分别为90.00%、65.00%、37.50%;手术治疗组1、2、3年生存率分别为88.89%、64.44%、40.00%。两组患者3年生存率比较差异无统计学意义(P>0.05)。结论体部伽玛刀治疗早期非小细胞肺癌的疗效与手术效果相当,它对于不能或不愿手术治疗的早期患者应是一种较好的治疗方法。 Objective To evaluate the clinical effects of body gamma knife radiotherapy and surgery tot early stage non-small cell lung cancer (NSCLC). Methods Eighty-five patients with early-stage NSCLC, who were treated in our hospital from 2000 to 2004 were analyzed retrospectively. Among them, 40 patients underwent body gamma knife and 45 received surgery. All patients were subjected to four cycles of adjuvant chemotherapy. Results One-, two-, three-year survival rate was 90. 00%, 65. 00%, 37. 50% for the patients receiving body gamma knife radiotherapy, and 88. 89%, 64. 44%, 40. 00% for those receiving surgery. There was no significant difference in three-year survival rate between the two therapies (P〉0. 05). Conclusion In terms of clinical effects, body gamma knife radiotherapy is equal to surgery for early-stage NSCLC. Body gamma knife radiotherapy is an ideal alternative to surgery for the patients with early-stage NSCLC who refuse to or cannot receive surgery.
机构地区 解放军 解放军
出处 《华南国防医学杂志》 CAS 2008年第6期10-12,共3页 Military Medical Journal of South China
关键词 非小细胞肺癌 放射疗法 体部伽玛刀 外科手术 Non-small cell lung cancer Radiotherapy Body gamma knife Surgery
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