中药结合股四头肌训练治疗膝骨性关节炎疗效观察

Effect of Traditional Chinese Drug Combined with Training of Musculus Quadriceps Fexoris on Knee Osteoarthritis

目的观察中药配合股四头肌训练治疗膝骨性关节炎(KOA)的临床康复效果。方法70例门诊KOA患者随机分为中药组和对照组,各35例。中药组以"身痛逐瘀汤"加味汤剂口服,2次/d;对照组应用舒林酸片0.2 g/次,2次/d。两组同时配合股四头肌训练,10次/疗程,共3个疗程,每疗程间隔3 d。应用足底压力步态分析检查和改良的日本骨科协会(JOA)评分法评价疗效。结果治疗后,中药组的效果优于对照组(P<0.05),在治疗结束12周后依然如此;中药组患者患肢的最大负重、时间积分、负重积分比例治疗后均明显改善(P<0.01),而对照组仅负重积分比例有改善(P<0.05)。结论采用中药配合股四头肌训练对KOA的疼痛和功能障碍均有较好的疗效。

Objective To observe the effect of traditional Chinese drug combined with training of rnusculus quadriceps fexoris on knee osteoarthritis （KOA）. Methods 70 out patient clinic KOA patients were divided randomly into the Chinese drug group and control group with 35 cases in each group. The Chinese drug group was treated with Shentongzhuyu medicinal broth PO bid; the control group was treated with Sulindac 0.2 g PO bid. Two groups were combined with the training of musculus quadriceps fexoris, having 10 times per course and 3 courses in total with a 3 days interval between two courses. The therapeutic effect was evaluated with footplate pressure gait analysis and modified JOA marks. Results After treatment, the effect of the Chinese drug group was superior to the control group （ P 〈0.05）, especially 12 weeks post treatment. There maximum weight loading, time integral and weight loading intergral of affected limb of the Chinese drug group significantly improved after treatment （ P 〈0. 01）, but for the control group, only weight loading intergral improved （ P 〈0. 05）. Conclusion Traditional Chinese drug combined with training of musculus quadriceps fexoris has better curative effect on the pain and functional disturbance of KOA.