抗宫炎片质量标准研究

Study on Quality Standard of Kanggongyan Tablets

目的:建立抗宫炎片质量控制标准。方法:采用薄层色谱法对方中的广东紫珠、益母草、乌药进行定性鉴别;用反相高效液相色谱法测定处方中广东紫珠有效成分木犀草素的含量。结果:在薄层色谱中可检出广东紫珠、益母草、乌药;木犀草素在4.75μg/ml—19.00μg/ml范围内呈良好的线性关系(R2=0.9998),平均回收率为100.2%,RSD为0.67%。结论:所建立的方法能准确地进行定性、定量检测,可用于该制剂的质量控制。

Objective ： To establish the quality standard of Kang gong yah tablets. Methods ： Adopting TLC to make a qualitative identification of Caulls et Folium Callicarpae, Herbe Leonuri and Radix Linderae in the prescription. Using HF-HPLC to determine Luteolin content of Guangdongzhizhu composition in the prescription. Results： Caulls et Folium Calliearpae, Herba Leonuri and Radix Linderae could be detected by TLC. The Luteolin, s showed good linear relationship（ R2 = 0.9998） in the range of 4.75μg/mL--19.00μg/mL and the average recovery was 100.2% with RSD of 0.67 % . Conclusion： The methods that were set up can make the qualitative and quantitative detection accurately, and use the quality control of the pharmaeeuties.