TTT治疗中心性浆液性脉络膜视网膜病变

Transpupillary thermotherapy for central serous chorioretinopathy at central macular region

目的观察经瞳孔温热疗法（traspupillary thermotherapy，TTT）治疗病变涉及黄斑中心区域的中心性浆液性脉络膜视网膜病变（centralserous chorioretinopathy，CSC）疗效和预后。方法对病变涉及黄斑中心区域的CSC患者18例18只眼进行TTT治疗，根据病灶大小选择光斑和能量。随访时复查视力、眼底，中心视野及FFA。结果治疗后患者视力、视野均明显好转，治疗后2月94．44％患者视力提高，平均视力及平均光敏感度（MS）分别为1．07和27．38dB，较TTT前差异有显著性（t=8．43、10．01；P〈0．01），FFA示所有病例渗漏均停止，但有2例复发。结论TTT治疗CSC简单有效，尤其适合病变涉及黄斑中心区域的CSC，无明显并发症。

Objective To investigate the clinical results of transpupillary thermotherapy for patients with central serous chorioretinopathy （CSC）at central macular region.Methods 18 cases （ 18 eyes）of CSC at central macular region diagnosed by FFA were treated with a diode laser at 810 nm.Laser parameters were as follow：the diameters of beam spot varied from 800μ m to 2000μm,the power from 100mW to 260mW,the duration 600s,beam spots from 1 to 2.The visual acuity,ophthalmoscopy,central visual field and FFA were followed up.Results The visual acuity and central visual field were improved after laser treatment.2 months after treatment the visual acuity increased in 17 eyes （94.44%）.The average visual acuity and mean sensitivity of 18 eyes were 1.07 and 27.38 dB respectively.The difference was significant （t =8.43,10.01 ;P 〈0.01 ）compared with the average visual acuity and mean sensitivity before the treatment.FFA showed that fluorescein leakage stopped in all eyes.But there were 2 recurrent cases during the follow-up time.Conclusions Transpupillary thermotherapy is one of the effective and secure therapies for CSC especially when the RPE lesion referred to the central macular region.