复方血栓通胶囊治疗视网膜分支静脉阻塞的眼底形态学变化

Effect of Oral Fufang Xueshuantong in treating of branch retinal vein occlusion：morphology changes analysis

目的从眼底形态学角度探讨复方血栓通胶囊治疗视网膜分支静脉阻塞的临床疗效。方法选取视网膜分支静脉阻塞患者72例（72只眼）随机分为复方血栓通治疗组和丹参治疗组。治疗前和治疗后1个月，分别行最佳矫正视力、视网膜分支静脉相对直径（d／D）和眼底出血相对面积（a／A）的测量。结果两组治疗后1个月，最佳矫正视力均明显提高（P〈0．01），d／D值均明显减小（P〈0．01），且均无组间差异（均P〉0．05）。治疗后两组a／A值均明显缩小（P〈0．01），但治疗后血栓通组a/A值（4．11±2．46）明显比丹参组a/A值（8．36±2．73）小（P〈0．01）。结论复方血栓通胶囊口服能有效提高视网膜分支静脉阻塞后的视力、缩容迂曲静脉、促进出血吸收。

Objective To evaluate the morphology changes after Fufang Xueshuantong treatment in branch retinal vein occlusion （BRVO）.Methods 72 eyes of 72 consecutive BRVO patients were randomly divided into Fufang Xueshuantong group and Danshen group.One month after treatment,best corrected visual acuity （BCVA）, relative retinal vein diameter （d/D）and relative retinal hemorrhage area （a/A）were measured and analyzed.Results One month after treatment,the BCVA parameters were improved and d/D parameters were decreased in both groups respectively （P 〈0.01 ）, and there were no inter-group differences of BCVA and d/D both before and after treatment.One month after treatment, a/A parameters were obviously decreased in both groups respectively （P 〈0.01 ）.Although there were no inter-group difference before treatment,the a/A parameter was more obviously decreased in the Fufang Xueshuantong group （4.11±2.46）than in the Denshen group （8.36 ± 2.73）.Conclusion In the branch retinal vein occlusion eyes,Fufang Xueshuantong could effectively improve the visual acuity, decrease the diameter of enlarged retinal vein and promote the absorption of the preretinal hemorrhage.