8Capell HA, Porter DR, Madhok R,et al. Second line (disease modifying) treatment in rheumatoid arthritis:which drug for which patient [ J] .? Ann Rheum Dis, 1993 ;52:423-8.
9Deal CL,Meenan RD,Goldenberg DL,et al. The clinical features of elderly-onset rheumatoid arthritis[ J]. Arthritis Rheum,1985 ;28:987-94.
10Hirshberg B, Muszkat M, Schlesinger O, et al. Safety of low dose methotrexate in elderly patients with rheumatoid arthritis[ J]. Postgrad Med J, 2000 ;76:787-9.
3Arnett FC,Edworthy SM,Bloch DA,et al.The american rheumatism association 1978 revised criteria for the classification of rheumatoid arthritis[J].Arthritis Rheum,1988,31(3):315~324.
4Palosuo T,Tilvis R,Strandberg T,et al.Filaggrin related antibodies among the aged[J].Annals of the Rheumatic Diseases,2003,62(3):261~263.
5Schellekens GA,Visser H,De Jong BAW,et al.The diagnostic properties of rheumatoid arthritis recognizing a cyclic citrullinated peptide[J]. Arthritis Rheum,2000,43(1):155~163.
6Bas S, Perneger TV,Seitz M,et al.Diagnostic tests for rheumatoid arthritis:comparison of anti-cycliccitrullinated peptide antibodies,anti-keratin antibodies and IgM rheumatoid factors[J].Rheumatology,2002,41(7):809~814.
7Lopez Hoyos M,Ruiz De Alegria C,Blanco R,et al.Clinical utility of anti-CCP antibodies in the differential diagnosis of elderly-onset rheumatoid arthritis and polymyalgia rheumatica[J].Rheumatology,2004,43(5):655~657.
9Girelli F,Foschi FG,Bedeschi E,et al.Is anti-citrullinated peptide a useful laboratory test for the diagnosis of rheumatoid arthritis[J] ? Allerg Immunol,2004 ;36 (4):127 -30.
10Lopez-Hoyos I,Ruiz de Alegria C,Blanco R,et al.Clinical utility of anti-ccp antibodies in the differential diagnosis of elderly-onset rheumatoid arthritis and polymyalgia rheumatica[ J].Rheumatology,2004;43(5):655-7.
5Schellekens GA, Visser H, De -Jong BAW, et al. The di-agnostic propoerties of rheumatoid arthritis antibodies rec-ognizing a cyclic citrullinated peptide[ J]. Arthritis Rheum, 2000;43(6) :155.
6GlennasA, Kvien TK, AndrupO, et al. Reeentonset arthritis in the elderly: a five year longitudinal observational study [ J].J Rheumato,2000;27:101 -108.
7Moffett SP,Oakley JI,Cauley JA,et al.Study of Osteoperotic Fractures Research Group.Osteoprotegerin Lys3Asn polymorphism and the risk of fracture in older women[J].J Clin Endocrinol Metab,2008;5 (12):1763-8.
8Roldan JF,Del Rincon I,Escalante A,et al.Loss of cortical bone from themetacarpal diaphysis in patients with rheumatoid arthritis:independent effects of systemic inflammation and glucocorticoids[J].J Rheumatol,2006;33(4):508-16.
9Kwan TS,Padrines M,Theoleyre S,et al.IL-6,RANKL,TNF-α /IL-1:Interrelations in bone resorption pathophysiology[J].Cytokine Growth Factor Rev,2004 ; 190 (2):.2-3.
10Arnett FC,Edworthy SM,Bloch DA,et al.The American Rheumatism As-sociation 1987 revised criteria for the classification of rheumatoid thrifts[J].Arthritis Rheum,1988;31(3):315-24.