以系列血清为基础的急性病毒性肝炎血清学诊断分析

Analyze the diagnosis of acute viral hepatitis based on serial serum

目的通过系列血清检测,分析临床急性病毒性肝炎诊断。方法收集急性病毒性肝炎住院病例病案,采集病例系列血清及粪便标本,采用ELISA方法检测病毒性肝炎血清标志物,RT-nPCR方法行粪便戊型肝炎病毒核酸检测。结果各型肝炎中临床最易在急性乙型肝炎和慢性乙型肝炎急性发作之间造成误诊。结论系列血清检测可提高临床病毒性肝炎诊断的准确性。

Objective Analyze the diagnosis of acute viral hepatitis based on serial serum. Methods The medical record, serial sera and feces of hospitalized acute viral hepatitis in this hospital were collected. Serum hepatitis markers and hepatitis E viral nucleic acid in patients/feces were detected respectively by ELISA and / or RT - nPCR. Results It most easily to misdiagnosis between acute hepatitis B and chronic hepatitis B acute episode in clinic. Conclusion The diagnosis to viral hepatitis may be more exacta in clinic by serial serum test.