摘要
瞄准:为了学习流行和风险因素,与人的免疫不全与三倍的感染联系了在一张城市的诊所人口的病毒(HIV )/hepatitis B (HBV )/hepatitis C 病毒(HCV ) 。方法:5639 个病人的回顾的图表评论在纽约城市里在圣卢凯斯鲁塞韦尔特医院 HIV 诊所(全面照顾的中心) 列在后面,从 1999 年 1 月的美国到 2007 年 5 月。下列人口统计的特征被分析:年龄,性别,种族和 HIV 冒因素的风险。多重逻辑回归分析被执行在这些病毒的获得上评估人口统计的因素的影响。结果:HIV/HBV, HIV/HCV 和 HIV/HBV/HCV 感染在 252/5639 (4.47%) 被检测, 1411/5639 (25.02%) 和 89/5639 (1.58%) 病人分别地。HIV/HBV 合作感染与男性被联系(或 1.711;P = 0.005 ) ,黑色跑(或 2.091;P 【
0.001 ) ,人与 \O 性交人(MSM )( 或 1.747;P = 0.001 ) ,静脉内的药使用(IDU )( 或 0.114;P 【
0.001 ) , IDU 和异性爱的活动(或 0.247;P = 0.018 ) ,或未知(或 1.984;P = 0.004 ) 。HIV/HCV 合作感染与男性被联系(或 1.241;P = 0.011 ) ,黑色跑(或 0.788;P = 0.036 ) , MSM (或 0.565;P 【
0.001 ) , IDU (或 8.956;P 【
0.001 ) , IDU 和异性爱的活动(或 9.106;P 【
0.001 ) , IDU 和 MSM (或 9.179;P 【
0.001 ) ,或输送(或 3.224;P 【
0.001 ) 。HIV/HBV/HCV 合作感染与男性被联系(或 2.156;P = 0.015 ) , IDU (或 6.345;P 【
0.001 ) , IDU 和异性爱的活动(或 9.731;P 【
0.001 ) , IDU 和 MSM (或 9.228;P 【
0.001 ) ,或未知(或 4.219;P = 0.007 ) 。结论:我们的学习证明有 HBV/HCV/HIV 的合作感染显著地与 IDU 被联系。这些结果加亮需要加强教育和综合照顾的最佳的模型,特别地为有 IDU 的人口,到减少病毒的传播的风险。
AIM: To study the prevalence and risk factors associated with triple infection with human immunodeficiency virus (HIV)/hepatitis B virus (HBV)/hepatitis C virus (HCV) in an urban clinic population. METHODS: Retrospective chart review of 5639 patients followed at St. Luke's-Roosevelt Hospital HIV Clinic (Center for Comprehensive Care) in New York City, USA from January 1999 to May 2007. The following demographic characteristics were analyzed: age, sex, race and HIV risk factors. A multiple logistic regression analysis was performed to evaluate the influence of demographic factors on acquisition of these viruses. RESULTS: HIV/HBV, HIV/HCV and HIV/HBV/HCV infections were detected in 252/5639 (4.47%), 1411/5639 (25.02%) and 89/5639 (1.58%) patients, respectively. HIV/HBV co-infections were associated with male gender (OR 1.711; P = 0.005), black race (OR 2.091, P 〈 0.001), men having sex with men (MSM) (OR 1.747, P = 0.001), intravenous drug use (IDU) (OR 0.114, P 〈 0.001), IDU and heterosexual activity (OR 0.247; P = 0.018), or unknown (OR 1.984, P = 0.004).HIV/HCV co-infections were associated with male gender (OR 1.241; P = 0.011), black race (OR 0.788; P = 0.036), MSM (OR 0.565; P 〈 0.001), IDU (OR 8.956; P 〈 0.001), IDU and heterosexual activity (OR 9.106; P 〈 0.001), IDU and MSM (OR 9.179; P 〈 0.001), or transfusion (OR 3.224; P 〈 0.001). HIV/HBV/HCV coinfections were associated with male gender (OR 2.156; P = 0.015), IDU (OR 6.345; P 〈 0.001), IDU and heterosexual activity (OR 9.731; P 〈 0.001), IDU and MSM (OR 9.228; P 〈 0.001), or unknown (OR 4.219; P = 0.007). CONCLUSION: Our study demonstrates that coinfection with HBV/HCV/HIV is significantly associated with IDU. These results highlight the need to intensify education and optimal models of integrated care, particularly for populations with IDU, to reduce the risk of viral transmission.
关键词
人体免疫缺陷病毒
人口统计学
乙肝
丙肝
Prevalence
Demographics
Human immunodeficiency virus
Hepatitis B
Hepatitis C