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爱维莫潘(alvimopan) 被引量:2

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机构地区 沈阳药科大学
出处 《中国药物化学杂志》 CAS CSCD 2008年第6期479-480,共2页 Chinese Journal of Medicinal Chemistry
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  • 1BUEHLER J D. Compositions containing opioid antagonists: US, 2007092576[ P]. 2007 - 04 - 26.
  • 2EVANS D A, MITCH C H, THOMAS R C, et al. Application of metalated enamines to alkaloid synthesis. An expedient approach to the synthesis of morphine-based analgesics[J ]. J Am Chem Soc, 1980,102(18) : 5955 - 5956.
  • 3BARNETT C J, COPLEY-MERRIMAN C R, MAKI J. Synthesis of picenadol via metalloenamine alkylation methodology [J ]. J Org Chem, 1989, 54 (20) : 4795 -4800.
  • 4MARON D J, FRY R D. New therapies in the treatment of postoperative ileus after gastrointestinal surgery [ J ]. Am J Ther, 2008, 15 (1) : 59 - 65.
  • 5WEBSTER L, JANSEN J P, PEPPIN J, et al. Alvimopan, a peripherally acting mu-opioid receptor (PAM-OR) antagonist for the treatment of opioid-induced bowel dysfunction:results from a randomized, double-blind, placebo-controlled, dose-finding study in subjects taking opioids for chronic non-cancer pain [J ]. Pain, 2008, 137(2) :428 - 440.

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