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ABVD-21方案治疗霍奇金淋巴瘤37例

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摘要 目的观察ABVD-21方案治疗霍奇金淋巴瘤(HL)的临床疗效和不良反应。方法多柔比星(ADM)25mg/m^2,静脉滴注,第1、8天;博莱霉素(BLM)10mg/m^2,肌肉注射,第1、8天;长春新碱(VCR)1.4mg/m^2,静脉滴注,第1、8天;氮烯咪胺(DTIC)375mg/m^2,静脉滴注,第1、8天;每21d重复,每例至少完成4个周期的化疗。结果全组37例患者均可评价疗效,CR33例(89.17%),PR2例(5.41%),SD1例(2.70%),PD1例(2.70%),总有效率(CR+PR)94.59%,3年无失败生存(FFS)81.08%,3年无复发生存(RFS)91.89%,3年总生存率(OS)94.59%,Ⅲ~Ⅳ度粒细胞减少仅8.10%。结论ABVD-21方案治疗HL有效率高,毒副作用可耐受,值得进一步应用。
出处 《肿瘤研究与临床》 CAS 2008年第12期855-856,共2页 Cancer Research and Clinic
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