Diffusion Coefficients of L-Arginine in Non-Newtonian Fluid

L-Arginine is an important component of amino acid injection. Its diffusion in body fluid and blood is of key importance to understand drug diffusion and drug release. As a fundamental demand for study and being a considerably valuable reference for application, in this study, the diffusion coefficients of L-arginine in polyacrylamide（PAM） aqueous solution used as non-Newtonian fluid similar to blood and body fluid were measured using a holographic interferometer. The effects of interaction among molecules and solution concentration on diffusion were analyzed and discussed, respectively. Based on the obstruction-scaling model, a novel modified model was presented for predicting diffusivity of solute in non-Newtonian fluid. Good agreement was achieved between the calculated value and the experimental data.

L 精氨酸是氨基酸注射的一个重要部件。它在身体液体和血的散开具有关键重要性理解药散开和药版本。作为对学习的一个基本要求并且是为申请的一本更加珍贵的参考书在这研究，在水的答案用作类似于血的非牛顿的液体和身体液体的 polyacrylamide (PAM ) 的 L 精氨酸的散开系数用 holographic 干涉仪被测量。在散开上的分子和答案集中之中的相互作用的效果分别地被分析并且讨论。基于可伸缩阻塞的模型，一个新奇修改模型为在非牛顿的液体预言溶质的扩散性被介绍。好同意在计算价值和试验性的数据之间被完成。