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治疗猪牛呼吸道疾病的新型兽用抗菌药物——泰拉霉素 被引量：9

Tulathromycin:a New Triamilide Antibiotic for Bovine and Porcine Respiratory Disease
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摘要 泰拉霉素是动物专用的新型大环内酯类抗生素,用于牛和猪呼吸系统疾病的防治。本文综述了泰拉霉素的抗菌活性、药动学、药效学、毒性及残留等方面的特点和研究概况,为该药在兽医临床上的应用提供了参考。 Tulathromyein is a novel triamilide antimicrobial that has been approved for use in the treatment and prevention of bovine and swine respiratory disease. This article is mainly about spectrum of activity, pharmacokinetics,pharmacodynamics, toxicity, residues and clinical use of this drug.
作者 高延玲 刘宏伟 班付国 赵海燕 巩丹
机构地区 河南省兽药监察所
出处 《中国兽药杂志》 2008年第12期51-54,共4页 Chinese Journal of Veterinary Drug
关键词 泰拉霉素 抗菌活性 药动学 药效学 残留 临床应用 tulathromycin spectrum of activity pharmacokinetics pharmacodynamics residues clinical use
分类号 S859.796 [农业科学—临床兽医学]
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参考文献18

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  • 2Reese C P,Norcia L J ,Skogerboe T L,et al. Time - killing Kinetics and Impact of Culture Conditions (pH , CO2 and serum) om MIC Values of Tulathromycin against Hameophilus Sonmus [ D ]. Proc 23rd World Buiatries Congr,2004:70 -71.
  • 3Nowakowski M A,Inskeep P B, Risk J E,et al. Pharmacokinetics and Lung Tissue Concentrations of Tulathromycin, a New Triamilide Antibiotic in Cattle[ J]. Vet Ther,2004, 5 (1) :60 - 74.
  • 4Benchaoui H A, Nowakowski M, Sherington J ,et al. Pharmacokinetics and Lung Tissue Concentrations of Tulathromycin in Swine [J]. Vet Pharmaeol Ther,2004,27(4) :203 -210.
  • 5Eberhard Scheuch A, Janina Spieker A, Monica Venner B, et al. Quantitative Determination of the Macrolide Antibiotic Tulathromycin in Plasma and Broncho - alveolar Cells of Foals Using Tandem Mass Spectrometry [ J].Journal of Chromatography B, 2007,850 : 464 - 470.
  • 6Nutsch R G, Hart F J, Rooney K A,et al. Efficacy of Tulathromycin Injectable Solution for the Treatment of Naturally Occurring Swine Respiratory Disease [ J ]. Vet Ther, 2005,6 ( 2 ) : 214 - 224.
  • 7McKelvie J,Morgan J H,Nanjiani I A,et al. Evaluation of Tulathromycin for the Treatment of Pneumonia Following Experimental Infection of Swine with Mycoplasma Hyopneumoniae [ J ]. Vet Ther,2005,6( 2 ) : 197 - 202.
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同被引文献71

  • 1安明,常珍,高雷,李眉.地红霉素的合成[J].中国抗生素杂志,2004,29(9):526-528. 被引量：6
  • 2李玮,郭腾,陈洪亮,禚宝山.兽用新型大环内酯类抗生素——土拉霉素(ulathromycin)[J].中国动物保健,2006,8(4):38-39. 被引量：7
  • 3宋福杰,刘明春,邹美,符特.兽用抗菌药物土拉霉素研究进展[J].兽药与饲料添加剂,2006,11(4):4-6. 被引量：8
  • 4Hammen, Lehner. Process for preparing 4"-substituted-9- deoxo-9a-aza-9a-homoerythromycin a derivatives : EP, 125- 3153A1 [ P]. 2002-10-30.
  • 5John Philip Dirlam, Hamish Alastair Irvine, Alan Elwood Blize. Macrolides : US ,6472371 B1 [ P]. 1998-12-21.
  • 6Brian S B, Michael A L, Bingwei V Y. 4"-substituted-9- deoxo-ga-aza-9a-homoerythromycin a derivatives : US, 6420536B1 [ P]. 1998-5-29.
  • 7郭强,周妮妮,董坤,等.一种制备泰拉霉素的新方法:CN,102260306[P].2011-7-22.
  • 8EBERHARD S A,JANINA S A,MONICA V B,et al.Quantitative determi-nation of the macrolide antibiotic tulathromycin in plasma and bronchoalve-olar cells of foals using tandem mass spectrometry[J].Journal of Chroma-tography B,2007,850(1/2):464-470.
  • 9BENCHAOUI H A,NOWAKOWSKI M,SHERINGTON J,et al.Pharmaco-kinetics and lung tissue concentrations of tulathromycin in swine[J].Vet-erinary Pharmacol and Therapeutics,2004,27(4):203-210.
  • 10EVANS N A.Tulathromycin:an overview of a new triamilide antimicrobial forlivestockrespiratory disease[J].Veterinary Therapeutics,2005,6(2):83-95.

引证文献9

二级引证文献20

中国兽药杂志
2008年 第12期

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