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慢性病贫血的分子机制研究进展 被引量:6

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摘要 慢性病贫血是由感染等因素引起的一种继发性贫血,其典型特征为血清铁含量下降和巨噬细胞铁滞留等,它的发生与铁调素的含量增加有关。该文对慢性病贫血的分子机制研究进展进行综述,供临床参考。
作者 郭晓强
出处 《新医学》 北大核心 2008年第12期832-833,共2页 Journal of New Medicine
基金 全军十一五青年基金资助项目(编号06Q097)
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参考文献23

  • 1SHARMA S, NEMETH E, CHEN Y H, et al. Involvement of hepcidin in the anemia of multiple myeloma[J]. Clin Cancer Res, 2008, 14 ( 11 ) : 3262 -3267.
  • 2ROY C N, ANDREWS N C. Anemia of inflammation: the hepcidin link [J]. Curr Opin Hematol, 2005, 12 (2): 107-111.
  • 3JURADO R L. Iron , infections, and anemia of inflammation[J]. Infect Dis, 1997, 25 (4): 888-895.
  • 4NEMETH E. Iron regulation and erythropoiesis [J].Curr Opin Hematol, 2008, 15 (3): 169-175.
  • 5ROY C N, MAK H H, AKPAN I, et al. Hepcidin antimierobial peptide transgenic mice exhibit features of the anemia of inflammation[J]. Blood, 2007, 109 (9): 4038-4044.
  • 6NICOLAS G, CHAUVET C, VIATTE L, et al. The gene encoding the iron regulatory peptide hepeidin is regulated by anemia, hypoxia, and inflammation[J]. J Clin Invest, 2002, 110 (7): 1037-1044.
  • 7NEMETH E, RIVERA S, GABAYAN V, et al. IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin[J]. J Clin Invest, 2004, 113 (9) : 1271-1276.
  • 8PIETRANGELO A, DIERSSEN U, VALLI L, et al. STAT3 is required for IL-6:gp130-dependent activation of hepcidin in vivo[ J]. Gastroenterology, 2007, 132 (1): 294-300.
  • 9WRIGHTING D M, ANDREWS N C. Interleukin-6 induces hepcidin expre-ssion through STAT3[J]. Blood, 2006, 108 (9) : 3204-3209.
  • 10VERGA FALZACAPPA M V, VUJIC SPASIC M, KESSLER R, et al. STAT3 mediates hepatic hepcidin expression and its inflammatory stimulation[J]. Blood, 2007, 109 (1) : 353-358.

二级参考文献3

  • 1Hector M, Burton JR. What are the psychiatric manifestations of vitamin B12 deficiency? [J]. J Am Geriatr Soc, 1988,36 (12):1105-12.
  • 2Allen RH. Megaloblastic anemias[A]. In: Cecil Texbook of Medicine[ M ], Bennett JC, Plum F, ed . 20th ed. Philadelphia: WB Sannders Company, 1996. 843-51.
  • 3程昌斌,曾庆曙,黄建尧,郝思国,任立奋,蔡学杰.323例老年人血液病骨髓检查分析[J].安徽医科大学学报,1998,33(4):300-301. 被引量:15

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