萝卜秦艽化学成分的研究(Ⅲ)

Chemical constituents of Phlomis medicinalis(Ⅲ)

目的研究萝卜秦艽Phlomis medicinalis的化学成分。方法采用各种现代色谱技术进行分离纯化,根据化合物的理化性质和波谱数据进行结构鉴定。结果从萝卜秦艽根的95%乙醇提取物中分离并鉴定了10个化合物,分别为1-去羟基山栀素甲酯(1-dehydroxyshanzhigenin methyl ester,Ⅰ)、钩萼草素A(notohamosin A,Ⅱ)、洋丁香苷(verbascoside,Ⅲ)、3,4-二羟基苯乙醇(Ⅳ)、琥珀酸(Ⅴ)、蔗糖(Ⅵ)、2,6-二聚果糖(Ⅶ)、果糖吡喃丁苷(Ⅷ)、D-葡萄糖(Ⅸ)和D-果糖(Ⅹ)。结论所有化合物Ⅱ均为首次从该植物中分离得到,其中化合物为首次从该属植物中分得,化合物Ⅰ为一新化合物。

Objective To study the chemical constituents of Phlornis medicinalis. Methods The constituents were isolated and purified by various modern chromatography techniques and the structures were elucidated by physicochemical properties and spectral analyses. Results Ten compounds were obtained and elucidated as 1-dehydroxyshanzhigenin methyl ester （ Ⅰ ）, notohamosin A （ Ⅱ ）, verbascoside （ Ⅲ ）, 3, 4-dihydroxyphenyl ethanol （ Ⅳ ）, succinic acid （ Ⅴ ）, sucrose （ Ⅵ ）, 2, 6-difructose （Ⅶ）, butyl-β-D-fructopyanoside （Ⅷ）, D-glucose （ Ⅸ ）, and D-fructose （ Ⅹ ）. Conclusion All the compounds are isolated from this plant for the first time, compound Ⅱ is obtained from the plants of Phlomis Linn. for the first time, and compound Ⅰ is a new one.