摘要
对虾白斑综合征病毒(White spot syndrome virus,WSSV)是一种可以引起养殖对虾暴发性死亡的传染性病原,由于其强烈的传染性和极高的致死率,使得人们在应对它时,必须侧重于早期的防控。近年的研究表明,对虾存在类免疫(quasi-immune)机制,而WSSV的重组蛋白可以诱导对虾产生抗病保护效应。目前有关对虾白斑综合征病毒亚单位疫苗的研究大多围绕诱导产生高效免疫应答能力的囊膜蛋白进行免疫接种方式来展开。文章对该领域研究成果做一综述,旨在为今后WSSV的防控提供参考。
White spot syndrome virus （WSSV） is a virulent pathogen known to infect various crustaceans. This virus brought great economic losses in world shrimp farming every year and had not been controlled completely till today. Recent research indicated that Penaeus shrimp have quasi-immune mechanism, and the recombinant protein can be used to induce protective effect. Nowadays,the research of white spot syndrome virus subunit vaccine mostly started in envelope protein immunization which induced high efficiency on the ability of the immune response. The paper summarized the former research achievements in this field in order to offer reference for prevention and treatment of WSS in the future.
出处
《动物医学进展》
CSCD
2008年第12期73-76,共4页
Progress In Veterinary Medicine
基金
国家高技术发展计划课题(2006AA100312)
国家重点基础研究项目(2006CB101801)
关键词
对虾白斑综合症病毒
囊膜蛋白
亚单位疫苗
White spot syndrome virus （WSSV）
envelope structural protein
subunit vaccin
