自体角膜缘干细胞移植联合术中应用丝裂霉素C治疗翼状胬肉的疗效观察

To observe the effect of using limbal stemcells autografe transplantation combined with mitomycin C in the treatment of pterygium.

目的观察自体角膜缘干细胞移植联合术中应用丝裂霉素C治疗翼状胬肉的临床疗效。方法 121例132眼行自体角膜缘干细胞移植联合术中应用丝裂霉素C,术后随访6～36个月,观察术后复发情况。结果 2例4眼术后8个月复发,3例3眼术后13个月复发,复发率5.3%。结论自体角膜缘干细胞移植联合术中应用丝裂霉素C治疗翼状胬肉能有效降低术后的复发率,效果明显值得临床推广。

Objective To observe the effect of using limbal stermcells autograft transplantation combined with mitomycin C in the treatment of pterygium. Methods We used limbal stermcells transplantation combined with mitomycin C in 132 eyes of 121 patients, the follow -up time after surgery ranged from 6 to 36 months. Results 4 eyes of 2 patients developed pterygium in 8 months after surgery, and 3 eyes of 3 patients had pterygium in 13 months after surgery, the recurrence rate was 5.3%. Conclusion The limbal stermcells autogran transplantation combined with mitomycin C in pterygium surgery can effectively decline the post operative recurrence rate, and is the ideal operation method in the treatment of pterygiunm.