期刊文献+

丙戊酸钠诱发高血氨性脑病1例 被引量:1

下载PDF
导出
摘要 丙戊酸盐类抗癫痫药物是治疗癫痫的常用药物,也用于精神疾病的辅助治疗。该药可诱发脑病,常发生在服药早期,停药可使症状消失。典型的临床表现为癫痫发作加重、意识障碍、共济失调及扑翼样震颤。本文报道1例在服用丙戊酸钠后发生丙戊酸脑病(valproate encephalopathy,VPE)的病案。
作者 李令臣 罗健
出处 《中国医学创新》 CAS 2008年第34期150-150,共1页 Medical Innovation of China
  • 相关文献

参考文献5

  • 1张小澍,鱼爱和.药源性神经系统疾病(一)[J].药物不良反应杂志,2005,7(3):203-208. 被引量:10
  • 2Marie-José C.C. Dealberto.Valproate-induced hyperammonaemic encephalopathy: review of 14 cases in the psychiatric setting[J].International Clinical Psychopharmacology.2007(6)
  • 3P. Parize,P. Beuret,C. Fischer.Une encéphalopathie au valproate sans hyperammoniémie[J].Annales francaises d’anesthesie et de reanimation.2007(12)
  • 4Wadzinski J,Franks R,Roane D,et al.Valproate-associated hyperammonemic encephalopathy[].J Am Board Fam Med.2001
  • 5Alqahtani S,Federico P,Myers RP.A case of valproate-induced hyperammonemic encephalopathy:look beyond the liver[].Canadian Medical Association Journal.2007

共引文献9

同被引文献26

  • 1Jaksch M, Klopstock T, Kurlemann G, et al. Progressive myoclonus epilepsy and mitochondrial myopathy associated with mutations in the tRNA (Ser (UCN)) gene.Ann Neurol,1998,44:635-640.
  • 2Canafoglia L, Franceschetti S, Antozzi C, et al. Epileptic phenotypes associated with mitochondrial disorders. Neurology,2001,56:1340-1346.
  • 3Dickerson BC,Hohzman D,Grant PE,et al.Case records of the Massachusetts General Hospital. Case 36-2005. A 61-year-old woman with seizure,disturbed gait,and altered mental status.N Engl J Med,2005,353:2271-2280.
  • 4Shoffner JM. Mitochondrial myopathy diagnosis. Neurol Clin,2000,18:105-123.
  • 5Simon DK, Johns DR. Mitochondrial disorders: clinical and genetic features.Annu Rev Med,1999,50:111-127.
  • 6Nakamura M,Yabe I,Sudo A,et al.MERRF/MELAS overlap syndrome:a double pathogenic mutation in mitochondrial tRNA genes.J Med Genet,2010,47:659-664.
  • 7Aharoni S,Traves TA,Melamed E,et al. MELAS syndrome associated with both A3243G-tRNALeu mutation and multiple mitochondrial DNA deletions.J Neurol Sci,2010,296:101-103.
  • 8Michelson D J,Ashwal S.The pathophysiology of stroke in mitochondrial disorders.Mitochondrion,2004,4:665-674.
  • 9Ohama E,Ikuta F.Involvement of choroid plexus in mitochondrial encephalomyopathy(MELAS).Acta Neuropathol,1987,75:1-7.
  • 10Iizuka T,Sakai F.Pathogenesis of stroke-like episodes in MELAS:analysis of neurovascular cellular mechanisms.Curt Neurovasc Res,2005,2:29-45.

引证文献1

二级引证文献3

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部